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在早期慢性闭角玻璃眼和早期垂体腺瘤患者中,OCT和OCTA参数的比较

Zhi Tan¹, Kai-Lun Lu², Wan-Cheng Zhang²

¹Radiology Department. Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China.

Scientific reports

|September 13, 2024

概括

光学连贯性断层扫描血管造影 (OCTA) 和光学连贯性断层扫描 (OCT) 可以区分早期慢性初级闭角玻璃眼 (CPACG) 与类似视野损伤的垂体腺瘤 (PA). 与PA患者相比,CPACG患者的血液流量减少,视神经结构较薄.

科学领域:

眼科医生眼科眼科
神经眼科神经眼科
医疗成像医学成像

背景情况:

早期诊断视神经疾病对于有效治疗至关重要.
在轻度视野缺陷的情况下,区分慢性初级闭角光眼 (CPACG) 和垂体腺瘤 (PA) 可能是具有挑战性的.
光学连贯断层扫描 (OCT) 和OCT血管扫描 (OCTA) 为结构和血管评估提供了先进的成像功能.

研究的目的:

评估OCT和OCTA参数在区分早期CPACG与早期PA的诊断价值.
为了比较CPACG和PA患者与类似视野损失 (平均缺陷>6dB) 之间的视觉盘和斑点的结构和血管变化.

主要方法:

在早期CPACG和早期PA患者中,对OCT和OCTA参数的回顾性分析.
两组之间视网膜血流密度 (OCTA) 和各种视网膜层厚度 (OCT) 的比较.
使用Z测试来评估诊断性能的统计分析.

主要成果:

与OCTA的PA患者相比,CPACG患者在多个光盘和斑点层中表现出明显较低的视网膜血流密度.
CPACG患者表现出比PA患者在OCT上更薄的环皮状视网膜神经纤维层 (CP-RNFL),状细胞层 (GCL),黄斑状细胞综合体 (GCC) 和内层 (IPL).
发现,OCTA和OCT参数的诊断性能在两组之间是相似的.

结论:

早期CPACG的特点是,与早期PA相比,血管性减少,视神经和黄斑结构较薄,即使有可比的视野损伤.
海外国家和地区和地区都是有价值的工具,用于区分早期的CPACG和PA.
在区分这两种情况方面,OCTA表现出与OCT相似的有效性.

关键词:

慢性初级闭角光眼 (CPACG) 是一种疾病.光学连贯性断层扫描 (OCT)光学连贯断层扫描血管学 (OCTA)下垂体腺瘤 (PA) 是一种

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