在营养不良的血液透析患者中,口服营养对日内分析的影响:一项随机试验
Bancha Satirapoj1, Tanin Apiyangkool2, Paramat Thimachai2
1Division of Nephrology, Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, 10400, Thailand. satirapoj@yahoo.com.
Scientific reports
|September 13, 2024
概括
在血液透析期间口服营养补充剂 (ONS) 改善了末期病 (ESRD) 患者的营养不良炎症评分 (MIS). 与透析间的ONS相比,内部透析的ONS显示出更大的MIS改善.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床营养学 临床营养学
- 生物化学 生物化学
背景情况:
- 血液透析患者中普遍存在营养不良,影响治疗结果.
- 如果营养摄入量不足,建议服用口服营养补充剂 (ONS).
- 评估不同ONS时间策略的有效性至关重要.
研究的目的:
- 在营养不良的血液透析患者中,比较内部透析ONS (INTRA-ONS) 与内部透析ONS (INTER-ONS) 的有效性.
- 评估ONS时间对营养不良炎症评分 (MIS) 和血清白蛋白水平的影响.
- 为末期病 (ESRD) 患者确定最佳的营养支持策略.
主要方法:
- 随机对照试验与32个营养不良的血液透析患者.
- 患者被分配到INTRA-ONS或INTER-ONS组,持续12周.
- 营养不良炎症评分 (MIS) 和血清白蛋白是主要结果指标.
主要成果:
- 无论是INTRA-ONS还是INTER-ONS,都显著减少了总的MIS.
- 与INTER-ONS相比,INTRA-ONS组显示MIS的减少明显更大.
- 血清白蛋白,饮食摄入量,人体测量或群体之间的体重没有显著差异.
结论:
- 内日分析ONS是一种可行的策略,用于改善营养状况营养不良的ESRD患者.
- 与INTER-ONS相比,INTRA-ONS在降低营养不良炎症评分方面表现出更高的有效性.
- 在血液透析患者的营养不良管理中,ONS时间可能发挥作用.
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