过早出生的成年人具有较低的外周骨肌肉区域和强度
Alyson Deprez1,2, Ramy El-Jalbout1, Anik Cloutier1
1Research Center, CHU Sainte-Justine, 3175 Chemin de la Côte-Sainte-Catherine, Montréal, QC, H3T 1C5, Canada.
Scientific reports
|September 13, 2024
概括
过早出生的成年人表现出较低的肌肉力量和较小的肌肉尺寸,与全日制对照相比. 这些发现表明,早产后骨肌肉的长期变化会影响整体健康.
科学领域:
- 生理学 生理学 生理学
- 发展生物学 发展生物学
- 肌肉骨健康 肌肉骨健康
背景情况:
- 过早生育会影响多个器官系统,可能会影响长期功能能力.
- 运动能力取决于心血管,肺和骨肌肉的综合功能.
- 之前的动物研究表明,随着早产相关的条件,成年后的肌肉缩.
研究的目的:
- 为了比较早产的成年人的骨肌肉组成和强度,与全程对照进行比较.
- 调查早产和成年人肌肉形态和功能之间的关联.
- 评估支气管肺功能障碍对早产成人肌肉特征的影响.
主要方法:
- 55名早产成人 (妊娠≤29周) 和53名满期对照的观察队列研究.
- 在休息和最大自愿收缩期间,对腿直骨进行肌肉骨超声波成像.
- 手动动力计测量手和腿的最大自愿收缩.
主要成果:
- 与对照人群相比,早产的成年人肌肉强度 (手握,膝盖伸缩器) 和肌肉面积明显较小.
- 在早产组中观察到肌肉度增加.
- 这些缺陷在有支气管肺功能障碍史的早产个体中更为明显.
结论:
- 过早生育与成年时骨肌肉组成,大小和功能的持久变化有关.
- 这些发现强调了需要进行干预来支持早产儿肌肉发育和功能.
- 在早产后优化肌肉健康对于改善长期健康至关重要.
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