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Updated: Jun 13, 2025

A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4
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A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4

Published on: March 10, 2018

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化学因子受体CXCR4与CXCL12和hBD-3结合的相互作用和动态

Jackson Penfield1, Liqun Zhang2

  • 1Chemical Engineering Department, Tennessee Technological University, Cookeville, TN, 38505, USA.

Communications chemistry
|September 13, 2024
PubMed
概括

这项研究揭示了化学因子受体CXCR4如何与CXCL12和hBD-3结合. 特定的hBD-3类似物激活CXCR4,提供了对受体动态和疾病机制的见解.

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