多发性硬化症中的耻辱和健康结果:系统性审查
Bradley Powell1, Roger Mills2,3, Alan Tennant4
1Psychology Department, Royal Holloway, University of London, Egham, UK. nkjt012@live.rhul.ac.uk.
BMC neurology
|September 13, 2024
概括
耻辱感在多发性硬化症 (MS) 中显著损害心理和身体健康. 这次审查在18项研究中发现了一致的证据,将耻辱与不良结果联系起来,包括抑郁症和生活质量下降.
科学领域:
- 神经学 神经学
- 心理学 心理学 心理学
- 公共卫生 公共卫生
背景情况:
- 耻辱感越来越被认为是导致多发性硬化症 (MS) 中残疾的一个重要因素.
- 了解耻辱对健康结果的影响对于有效的MS管理至关重要.
- 本综述探讨了多发性硬化症患者的心理和身体健康与耻辱的关联程度.
研究的目的:
- 系统地审查和综合关于成年人患MS的耻辱和心理/身体健康结果之间的关联的证据.
- 确定污名化在多发性硬化患者群体中影响各种健康领域的程度.
主要方法:
- 在2023年11月,在PubMed,PsycINFO和Science Direct进行了系统的文献搜索.
- 纳入标准侧重于MS或临床隔离综合征的成年人的原始定量研究,衡量耻辱和健康结果.
- 使用Joanna Briggs研究所的批判性评估工具评估了方法质量和偏差风险.
主要成果:
- 确定了18项涉及22 021名患有多发性硬化症的参与者的研究.
- 在所有包括的研究中,在耻辱和不良的心理和身体健康结果之间发现了一致和显著的关联.
- 在超过一半的审查研究中,耻辱症与抑郁症和生活质量下降有显著的关联.
结论:
- 耻辱感与MS患者的心理和身体健康状况较差有显著的联系.
- 局限性包括西方白人参与者占主导地位,缺乏标准化的耻辱度量,排除了元分析.
- 需要进一步的研究来制定共识措施,并了解MS中耻辱的动态.
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