总体肌肉脂肪比率与甲状腺疾病风险之间的关联:一个横截面研究
Ziming Wang1,2, Mingfei Li1,2, Yifan Miao1,2
1Emergency Department, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China.
BMC public health
|September 13, 2024
概括
较高的干与大腿骨比率 (tMFR) 与甲状腺疾病 (TD) 的风险降低有关. 这项研究表明tMFR可能比BMI更好地预测TD,但需要更多的研究.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 肥胖问题研究研究
背景情况:
- 甲状腺疾病 (TD) 在美国是一个重大的健康问题.
- 肥胖是一个已知的TD风险因素,身体质量指数 (BMI) 是一个常见但有限的衡量标准.
- 骨干与大腿比率 (tMFR) 是一种新兴的肥胖指数,提供了比BMI更细致的评估.
研究的目的:
- 调查干部与大腿比率 (tMFR) 与甲状腺疾病 (TD) 风险之间的关联.
- 为了比较tMFR与甲状腺疾病的身体质量指数 (BMI) 的预测能力.
主要方法:
- 利用NHANES数据库 (2011-2018) 进行全面的调查和数据分析.
- 采用多重物流回归,平滑曲线拟合和子组分析.
- 包括11,912名受试者来评估tMFR和TD风险之间的关系.
主要成果:
- 总共分析了11,912名受试者,TD的患病率为7.14%.
- 发现tMFR和TD风险 (OR=0.90) 之间的反相关性.
- 在最高的tMFR四分位数中的个体与最低的四分位数相比,TD的风险降低了28% (OR=0.72).
- 与BMI相比,tMFR显示TD的预测能力优于TD.
结论:
- 干与大腿比率 (tMFR) 与甲状腺疾病 (TD) 的风险之间存在负相关性.
- 这些发现表明tMFR可能是TD风险评估的有价值指标.
- 建议进行进一步的前性研究来验证这些结果.
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