中枢神经系统儿科多学科瘤委员会:一个中心的经验
Rosellina Russo1, Tommaso Verdolotti2, Alessandro Perna2
1ARC Advanced Radiology Center (ARC), Department of Oncological Radiotherapy, and Hematology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy. rosellina.russo@policlinicogemelli.it.
BMC cancer
|September 13, 2024
概括
儿科神经瘤学多学科瘤委员会 (MTB) 通过加强合作,改善患者护理. 神经放射学家的投入显著影响了儿童脑瘤病例的治疗变化.
科学领域:
- 在瘤学瘤学.
- 儿科神经瘤学 儿科神经瘤学
- 医疗成像医学成像
背景情况:
- 多学科瘤委员会 (MTB) 对于优化癌症诊断和治疗策略至关重要.
- 有限的文献存在于MTBs的应用和影响,特别是在儿科神经瘤学中.
- 儿科脑瘤遗传学的最新进展需要更新的协作方法.
研究的目的:
- 描述一个研究所的儿科神经瘤多学科瘤委员会 (pnMTB) 的结构和功能.
- 评估 pnMTB 对患者管理和治疗决策的影响.
- 评估神经放射学家在pnMTB框架内的具体作用和贡献.
主要方法:
- 在2002年至2024年期间对儿科神经瘤学MTB进行文献综述.
- 从2019年到2022年在pnMTB上提出的236例患者病例 (107例患者) 的回顾性分析.
- 使用了基平方和t测试,分别用于定性和定量变量分析.
主要成果:
- 文献审查发现只有7篇论文,重点关注儿童中枢神经系统瘤的多学科方法.
- 在分析的队列中 (平均年龄为14.3岁),儿科瘤学家和神经外科医生是神经放射学家的主要推者 (70.3%).
- 建议的干预措施包括成像随访 (47.8%) 和化疗 (34.7%),神经放射学家的投入导致了72.4%的治疗变化.
结论:
- 该pnMTB增强了小儿中枢神经系统瘤管理专家之间的协调.
- 董事会促进当前治疗方案的实施和知识交流.
- 在pnMTB内部的协作性和专家投入显著改善了患者护理途径.
相关概念视频
Treatment Resistant Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Treatment Resistent Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...


