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活体捐赠者切除术的侧面性:它是否对捐赠后怀孕有泌尿学影响?
Ahmed Farouk Donia1,2, Eman Elrefaie3, Ayman Refaie3
1Nephrology and transplant unit, urology and nephrology center, Mansoura University, Mansoura, Egypt. afdonia@hotmail.com.
BMC urology
|September 13, 2024
概括
我们的研究表明,在绝经前妇女中切除右可能无法预防尿路感染 (UTI) 或怀孕期间的问题. 目前有利于左切除的政策可能是不必要的,需要进一步的研究.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 移植 移植 移植 移植
背景情况:
- 该中心的政策有利于在绝经前活捐赠者的右切除,因为担心捐赠后的妊娠并发症.
- 担忧包括尿管阻塞和尿路感染 (UTI) 在女性与一个孤独的右脏.
- 只有有限的研究支持或反驳这一政策.
研究的目的:
- 为了评估右与左切除术对绝经前活体脏捐赠者的捐赠后怀孕结果的影响.
- 为了比较经过右侧或左侧切除术的捐赠者之间尿道问题和功能的发生率.
主要方法:
- 对100名活着的脏捐赠者进行了回顾性分析,这些捐赠者在捐赠后怀孕.
- 捐赠者分为右切除术 (n=60) 和左切除术 (n=40) 组.
- 捐赠前和捐赠后的临床,实验室和超声数据的比较,包括尿路投诉和功能.
主要成果:
- 在这两组中都没有报告过捐赠后急性肌炎的病例.
- 右切除组显示,怀孕期间尿路感染减少的趋势不显著.
- 阻塞性尿路病变和末期病仅在右侧切除组 (分别是两个和一个捐赠者) 中观察到.
- 在捐赠后,功能在两组之间都是可比的.
结论:
- 在绝经前妇女中偏好左切除的政策可能过于谨慎.
- 在怀孕期间阻塞性泌尿病和尿路感染的潜在风险在右侧切除术后似乎没有显著增加.
- 建议进行更大规模的研究,以最终评估活捐赠者的右与左切除术的安全性和结果.
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