在PRKCZ未翻译区域的遗传多态性影响mRNA结构,稳定性和结合点

Aneela Mustafa1, Maria Shabbir2, Yasmin Badshah1

  • 1Department of Healthcare BiotechnologyAtta-Ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), Sector H-12, Islamabad, 44000, Pakistan.

BMC cancer
|September 13, 2024
PubMed
概括

蛋白激酶C Zeta (PRKCZ) 基因影响转录因子和miRNA结合的未翻译区域 (UTR) 的遗传变异. 这项研究确定了有害的PRKCZ变异及其对基因调节的影响,为治疗策略铺平了道路.

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