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Updated: Jun 13, 2025

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异常的SWI/SNF复合体成员在罕见的卵巢恶性瘤中占主导地位 - - 治疗耐药亚型中的治疗脆弱性

Yue Ma1, Natisha R Field1, Tao Xie1

  • 1Translational Oncology Group, School of Life Sciences, Faculty of Science, University of Technology Sydney, Ultimo, NSW 2007, Australia.

Cancers
|September 14, 2024
PubMed
概括

SWI/SNF复合体中的突变在卵巢癌,如OCCC和SCCOHT中很常见. 针对这些SWI/SNF通路改变,为这些罕见的癌症提供了新的治疗策略.

关键词:
在 ARID1A 中.在 ARID1B 里面,你会看到 ARID1B.在BAF染色体重塑复合物中,这就是SMARCA2的标志.这就是SMARCA4的标志.在SWI/SNF染色体重塑复合体中.卵巢小细胞癌的卵巢癌.子宫内膜状卵巢癌 (EnOC) 是一个子宫内膜异位症是什么?子宫内膜异位症是什么这种类型的高血症 (SCCOHT)卵巢透明细胞癌 (OCCC) 是一种癌症.

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