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Updated: Jun 13, 2025

Müller Glia Cell Activation in a Laser-induced Retinal Degeneration and Regeneration Model in Zebrafish
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盖莱克-1减弱了视网膜色素上皮细胞中PDGF介导的AKT信号传递

Martina Bizzotto1, Annabella Ostermaier1, Caspar Liesenhoff1

  • 1Department of Ophthalmology, University Hospital, LMU Munich, Mathildenstrasse 8, 80336 Munich, Germany.

International journal of molecular sciences
|September 14, 2024
PubMed
概括

加勒-1 降低了视网膜色素上皮细胞 (RPE) 中的血小板衍生生长因子 (PDGF) 介导的 AKT 信号传递和增殖. 这种效应与PDGF受体β (PDGF-Rβ) 的表达下降有关.

关键词:
在AKT信号传输中.这是ARPE-19的ARPE-19.在ERK的信号传输中.据PDGF的说法,这是一个很好的方法.在PDGF-Rββ中.盖莱克-1的使用情况加勒丁-1 缺乏症这就是PAKTT的协议.帕克 (Perk) 的意思是视网膜色素表皮细胞细胞

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