应用分子建模来设计具有强大的抗癌活性的创新型非对称CXCR4抑制剂

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Updated: Jun 13, 2025

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Miquel Martínez-Asensio1, Lluís Sàrrias1, Gema Gorjón-de-Pablo1,2

  • 1Grup de Química Farmacèutica, IQS School of Engineering, Universitat Ramon Llull, Via Augusta 390, E-08017 Barcelona, Spain.

International journal of molecular sciences
|September 14, 2024
PubMed
概括

研究人员使用分子建模探索了用于扩散大B细胞淋巴瘤 (DLBCL) 的新型CXCR4抑制剂. 一个虚拟图书馆产生了有前途的化合物,包括一种合成可行的候选物,该候选物对DLBCL有显著的体外活性.

关键词:
在CXCR4中,CXCR4是最常见的.DLBCL DLBCL 是一个字母.分子设计分子设计.虚拟选 虚拟选 虚拟选

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