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Updated: Jun 13, 2025

Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts
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探索来自Celastraceae物种的基或-三聚的抗癌潜力

Carolina P Reyes1, Alejandro Ardiles2, Laura Anaissi-Afonso3

  • 1Instituto Universitario de Bio-Orgánica Antonio González, Departamento de Bioquímica Microbiología, Biología Celular y Genética, Universidad de La Laguna, Av. Astrofísico Francisco Sánchez 2, 38206 La Laguna, Spain.

International journal of molecular sciences
|September 14, 2024
PubMed
概括

来自Celastraceae植物的新型基诺三烯显示出显著的抗瘤活性. 三种化合物对多个人类癌症细胞系表现出强烈的细胞毒性,其中核死被确定为主要的作用机制.

关键词:
塞拉斯特斯 (Celastrus vulcanicola) 是一个火山.梅斯 (Maytenus) sp. 这种植物有很多种.在Saccharomyces cerevisiae模型中.抗癌特征 抗癌特征这种类型的 celastroloids.人类瘤细胞系的细胞系.活细胞成像 活细胞成像

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