罗马尼亚儿科患者群体的表征 患有异性食道炎的罗马尼亚儿科患者群体的表征
Iulia Florentina Tincu1,2, Luiza Elena Bordei1,2, Lucica Luminita Gales2
1Department of Paediatrics, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
儿科异性食道炎 (EOE) 经常呈现异常. 早期诊断需要意识到诸如 regurgitation 和 dysphagia 这样的症状,以及高血红蛋白和IgE水平,特别是在耐火病例中.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 过敏和免疫学 过敏和免疫学
- 胃肠道病理 胃肠道病理
背景情况:
- 全球儿科埃索诺菲尔性食道炎 (EoE) 发病率的增加需要更好的理解.
- 儿童的EoE诊断需要与其他食道疾病 (如逆流性食道炎) 进行区分.
- 三级儿科中心在诊断和管理复杂的儿科胃肠道疾病方面发挥着至关重要的作用.
研究的目的:
- 分析儿科EOE的临床,生化和内镜特征.
- 为了在儿科队列中比较EoE病例与非eosinophilic食道炎.
- 在患有食道功能障碍的儿童中确定诊断EoE的关键指标.
主要方法:
- 对患有食道症状的儿童进行食道胃肠腺镜检查和活检的前性研究.
- 患者被分为EoE (第一组) 和反流食道炎 (第二组).
- 收集的数据包括临床表现,生化标志物 (eosinophilia,IgE) 和内镜检测结果.
主要成果:
- 确定了17例EoE病例和55例反流食道炎病例.
- 在EoE组中观察到男性占主导地位 (71%).
- 在EoE患者中,埃索诺菲利亚 (58.85%与18.18%) 和总IgE升高 (64.70%与10.9%) 显著高于EoE患者.
结论:
- 儿科胃肠科医生必须识别非典型的EoE表现.
- 活检对于诊断EoE至关重要,特别是在患有耐火性GERD类症状,消化不良或食物玻尿酸冲击的儿童中.
- 需要进行纵向研究,以调查儿科EOE的预后和治疗反应.
更多相关视频
10:15Conditional Reprogramming of Pediatric Human Esophageal Epithelial Cells for Use in Tissue Engineering and Disease Investigation
Published on: March 22, 2017
08:44Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation
Published on: May 30, 2020
相关概念视频
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Gastroesophageal Reflux Disease I: Meaning and Pathophysiology
