亚临床甲状腺功能低下症与辅助生殖技术中不良妊娠结果之间的关联单独怀孕:回顾性研究

亚临床甲状腺功能低下症与辅助生殖技术中不良妊娠结果之间的关联单独怀孕:回顾性研究

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Yuichiro Narita¹, Hiroyuki Tsuda¹, Eri Tsugeno¹

¹Department of Obstetrics and Gynecology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya 453-8511, Japan.

Journal of clinical medicine

|September 14, 2024

概括

在辅助生殖技术 (ART) 怀孕中,亚临床甲状腺功能低下症 (SCH) 会增加34周前早产的风险. 利沃甲状腺素治疗显著降低了这种风险,突出显示了甲状腺查的重要性.

科学领域:

生殖内分泌学生殖内分泌学
孕产妇和胎儿医学孕产妇和胎儿医学
甲状腺学甲状腺学

背景情况:

亚临床甲状腺功能低下症 (SCH) 与孕妇产周风险增加有关.
在辅助生殖技术 (ART) 单独怀孕中SCH对结果的影响需要进一步调查.

研究的目的:

评估SCH与ART单独怀孕中产周期结局之间的关联.
评估Levothyroxine治疗在减轻与SCH相关的风险方面的疗效.

主要方法:

对650例ART单项怀孕的回顾性分析 (2020年1月至2023年7月).
定义SCH为TSH>2.5mU/L与正常的自由T4.
在正常甲状腺功能,未经治疗的SCH和治疗的SCH组中比较结果 (早产,孕前,FGR).

主要成果:

在34周之前的早产率在未经治疗的SCH (B组) 与正常的甲状腺功能 (A组) 相比显著更高.
与A组相比,Levothyroxine治疗 (C组) 显著降低了34周前早产率.
较高的TSH水平与34周前早产率的增加相关.

结论:

在ART怀孕中,SCH与34周前早产率显著增加有关.
在这个人群中,Levothyroxine疗法充当了对早产早产的重要保护因素.
在ART怀孕中,普遍的甲状腺功能查和及时的激素治疗可能会减少产周并发症.

关键词:

艺术艺术艺术艺术莱沃西的治疗方法过早分娩过早分娩是什么亚临床的甲状腺功能低下症甲状腺刺激激素激素是什么

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