益生菌在性阴道候群病的管理
Karolina Akinosoglou1,2, Georgios Schinas1, Eleni Polyzou1
1Department of Medicine, University of Patras, 26504 Rio, Greece.
Journal of clinical medicine
|September 14, 2024
概括
益生菌对管理 vulvovaginal candidosis (VVC) 和预防复发有希望,尽管结果不一致. 可纳在急性治疗中更有效,但联合治疗和益生菌用于预防提供了好处.
科学领域:
- 妇科 妇科医生 妇科
- 微生物学 微生物学
- 药理学 药理学是指药理学的学科.
背景情况:
- Vulvovaginal candidosis (VVC) 是一种常见的阴道感染,通常对标准的抗真菌治疗有抗性.
- 复发性VVC (rVVC) 是一个重大挑战,需要替代或辅助疗法.
- 益生菌正在成为VVC管理的潜在治疗策略.
研究的目的:
- 综合审查益生菌在VVC治疗和预防中的作用和应用.
- 根据现有临床证据,评估益生菌在管理VVC和rVVC方面的疗效.
主要方法:
- 一个系统的文献搜索确定了相关的临床试验和对VVC益生菌的系统审查.
- 分析包括25项临床研究和7项系统性审查,检查治疗和预防结果.
- 研究对益生菌干预措施的有效性,安全性和耐受性进行了选.
主要成果:
- 益生菌对VVC的临床和真菌学反应产生了普遍积极但不一致的影响.
- 对于急性VVC治疗,可纳仍然优越;与益生菌的联合治疗可以减少复发.
- 益生菌似乎是安全的,并且可以很好地容忍VVC预防,改善阴道健康和减少症状.
结论:
- 益生菌为VVC提供低风险的辅助或替代方法,特别是用于预防复发.
- 不一致的发现需要进一步研究,因为研究设计,种群和益生菌配方各不相同.
- 未来的研究应该专注于特定的益生菌应用:独立的急性治疗,辅助疗法和rVVC预防.
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