慢性阻塞性肺部疾病患者的心血管风险:系统性审查
Ana Sá-Sousa1,2, Cidália Rodrigues3, Cristina Jácome1,2
1MTG Research and Development Lab, 4200-604 Porto, Portugal.
Journal of clinical medicine
|September 14, 2024
概括
患有慢性阻塞性肺病 (COPD) 的患者面临显著更高的心血管疾病 (CVD) 风险. 这一系统性审查强调了心脏病发作和心力衰竭等疾病的风险增加,强调了对COPD患者进行主动心血管监测的必要性.
科学领域:
- 肺部医学 肺部医学
- 心脏病学 心脏病学
- 流行病学 流行病学
背景情况:
- 慢性阻塞性肺病 (COPD) 是一个主要的全球健康问题.
- 患有COPD的患者表现出更高的心血管疾病 (CVD) 相关疾病的患病率.
- 对COPD患者的心血管疾病风险进行全面审查对于改善患者的治疗结果至关重要.
研究的目的:
- 系统地审查和综合有关COPD诊断患者各种心血管疾病风险的证据.
- 量化COPD与特定心血管疾病 (包括心肌梗塞,心力衰竭和中风) 之间的关联.
主要方法:
- 在PubMed,Web of Science和SCOPUS数据库中进行系统的文献搜索,截至2023年9月.
- 包括成人COPD患者 (GOLD标准,螺旋计或医生诊断) 报告心血管疾病风险的观察性研究.
- 来自24项涉及超过340万COPD患者和3100万对照患者的研究数据的叙述综合.
主要成果:
- 患有COPD的患者具有显著更高的整体心血管疾病,心肌梗塞 (MI),缺血性心脏病 (IHD),心力衰竭和胸痛风险.
- 对于心房动 (AF),中风,心脏突然死亡,肺高血压和外周血管疾病也观察到较高的风险,尽管证据各不相同.
- 大多数被纳入的研究 (17/24) 都是在欧洲进行的.
结论:
- 与一般人群相比,COPD患者患心血管疾病的风险较高.
- 密切监测心血管风险因素和有针对性的干预措施对于管理COPD患者至关重要.
- 本次审查强调需要综合护理策略,解决COPD和CVD管理.
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