在稀释水溶液中的兰坦化酸盐的物理化学特征和抗菌特性
Galina Kuz'micheva1, Alexander Trigub2, Alexander Rogachev2
1Research and Educational Center "Multi-scale Materials Engineering", MIREA-Russian Technological University, 119454 Moscow, Russia.
Molecules (Basel, Switzerland)
|September 14, 2024
概括
这项研究研究了化酸溶液,揭示了结构变化和抗菌性质. 溶液中的兰化物离子表现出协调变化,在较高度下,特定离子表现出抗菌和抗真菌活性.
科学领域:
- 无机化学 无机化学 有机化学
- 材料科学 材料科学 材料科学
- 生物化学 生物化学
背景情况:
- 兰化酸盐 (Ln(NO3) 3 · xH2O) 在各种化学应用中广泛使用.
- 了解这些化合物的溶液行为和生物活性对于它们的有效利用至关重要.
- 之前的研究集中在兰坦化物的结构性质上,但它们在水溶液中的抗菌作用需要进一步研究.
研究的目的:
- 描述在稀释水溶液中的兰坦化离子的局部结构.
- 为了研究酸盐组与兰坦化离子的协调.
- 为了评估兰坦化酸盐溶液的抗菌和抗真菌活性.
主要方法:
- 采用X射线衍射 (XRD) 和X射线吸收光谱学 (XAS:EXAFS/XANES) 来研究溶液和固态中类离子的局部结构.
- 红外 (IR) 光谱和pH测量被用来分析化学环境和溶液的特性.
- 进行了抗微生物测试,以确定各种酸兰坦化溶液的抗菌和抗真菌功效.
主要成果:
- EXAFS光谱检测显示,在溶解后,兰化离子在序列中间的第一个协调球的显著收缩.
- 发现酸盐组与双和单两种形式的化物离子协调,从到的数量越来越多.
- 对于化酸溶液,观察到度依赖的抗菌活性,在较高度下对特定化物 (Ce, Sm, Gd, Tb, Yb) 具有显著的抗菌和抗真菌作用,除了20毫米的Yb外.
结论:
- 化酸盐的溶解导致化离子协调球的结构变化.
- 酸盐连接体的协调模式和数量在兰他尼德系列中各不相同.
- 兰他尼德酸盐溶液表现出显著的抗菌性质,受特定的兰他尼德元素,度和pH值的影响,突出其在生物杀伤剂应用中的潜力.
更多相关视频
相关概念视频
01:261° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Overview
3.3K
Nitrous acid and nitric acids are two types of acids containing nitrogen, among which nitrous acid is weaker than nitric acid. Nitrous acid with a pKa value of 3.37 ionizes in water to give a nitrite ion and the hydronium ion.
The nitrous acid is unstable. Hence, it is formed in situ from a solution of sodium nitrite and cold aqueous acids such as hydrochloric or sulfuric acid. In an acidic solution, the –OH group of nitrous acid undergoes protonation to give oxonium ion, followed by...
The nitrous acid is unstable. Hence, it is formed in situ from a solution of sodium nitrite and cold aqueous acids such as hydrochloric or sulfuric acid. In an acidic solution, the –OH group of nitrous acid undergoes protonation to give oxonium ion, followed by...
3.3K
01:371° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Mechanism
3.7K
Nitrous acid is a relatively weak and unstable acid prepared in situ by the reaction of sodium nitrite and cold, dilute hydrochloric acid. In an acidic solution, the nitrous acid undergoes protonation when it loses water to form a nitrosonium ion—an electrophile. Nitrous acid reacts with primary amines to give diazonium salts. The reaction is called diazotization of primary amines.
3.7K
00:43Complexometric Titration: Ligands
926
Different monodentate and polydentate ligands are used as complexing agents in complexometric titration reactions. The formation of complexes by mono- and bidentate ligands involves two or more intermediate steps, limiting their use as complexing agents. In comparison, polydentate ligands can form complexes with metal ions in a single-step process, facilitating sharper end points. This means polydentate ligands, such as amino carboxylic acid derivatives, are most commonly employed in...
926
01:202° Amines to N-Nitrosamines: Reaction with NaNO2
4.1K
Secondary amines react with nitrous acid to form N-nitrosamines, as depicted in Figure 1. Nitrous acid, a weak and unstable acid, is formed in situ from an aqueous solution of sodium nitrite and strong acids, such as hydrochloric acid or sulfuric acid, in cold conditions. In the presence of an acid, the nitrous acid gets protonated. The subsequent loss of water results in the formation of the electrophile known as nitrosonium ion.
4.1K
01:14Photoluminescence: Applications
383
Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
383
01:19Ionic Strength: Effects on Chemical Equilibria
1.4K
The addition of an inert ionic compound increases the solubility of a sparingly soluble salt. For example, adding potassium nitrate to a saturated solution of calcium sulfate significantly enhances the solubility of calcium sulfate. Le Châtelier's principle cannot predict this shift in the equilibrium. Instead, this could be explained in terms of changes in the effective concentration of the ions in solution in the presence of added inert salt.
In this solution, the primary...
In this solution, the primary...
1.4K