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Updated: Jun 13, 2025

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
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通过3D药基重定位选活动识别含有新型基蛋白4 (BRD4) 结合物的新型基蛋白4 (BRD4) 结合剂

Ester Colarusso1, Erica Gazzillo1, Eleonora Boccia1

  • 1Department of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Italy.

Molecules (Basel, Switzerland)
|September 14, 2024
PubMed
概括

一个新的3D药模型用于含有odomain的蛋白4 (BRD4) 确定了强大的抑制剂. 这种药物重新定位策略成功地发现了具有高亲和性和选择性的新BRD4结合剂.

关键词:
抗癌剂是一种抗癌剂.类蛋白质是一种类蛋白质.化学合成 化学合成计算技术是指计算技术.发现药物的发现.药物重新定位 药物重新定位

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