库尔库明加载双油水油乳液的成分优化及其稳定性评估
Kristýna Opustilová1, Barbora Lapčíková1, Karolina Kocourková1
1Faculty of Technology, Department of Food Technology, Tomas Bata University in Zlin, Nam. T. G. Masaryka 5555, 760 01 Zlin, Czech Republic.
Molecules (Basel, Switzerland)
|September 14, 2024
概括
使用Tween 20,温度和均质化的优化油-水-油 (O/W/O) 乳液被开发用于黄素的输送. 外部阶段的子油产生了最稳定的乳液,在50天内粒子大小最小增加.
科学领域:
- 食品科学与技术 食品科学与技术
- 材料科学 材料科学 材料科学
- 制药科学 制药科学
背景情况:
- 多重乳液 (O/W/O) 提供了封装类化合物 (如黄素) 的潜力.
- 优化准备参数对于实现稳定和高效的交付系统至关重要.
研究的目的:
- 为了优化O/W/O乳液的制备,用于黄素封装.
- 评估外相油和储存对乳液稳定性和黄素输送的影响.
主要方法:
- 优化Tween 20的度 (0.5%),均质化速度 (10,000 RPM) 和温度 (25 °C).
- 分析不同外相油的乳液的物理化学和粘弹性特性.
- 在50天内监测稳定性和封装效率.
主要成果:
- 最佳准备涉及0.5%Tween 20,10,000 RPM均化在25 °C. 在25 °C的温度下.
- 含有各种食用油的乳液显示出出色的稳定性和封装效率.
- 外部阶段的子油产生了最稳定的乳液,具有最小的颗粒大小和最小的效率损失.
结论:
- 建立了一种可靠的方法来制备稳定的O/W/O乳液,用于黄素的输送.
- 在稳定的多重乳液配方中,子油是外部阶段的有希望的候选者.
- 这些发现为开发有效的生物活性化合物输送系统提供了洞察力.
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