基于坎和芬科尔的疏水性乳用溶剂的表征及其在化物提取中的应用
Alexander Kaufmann1, Lars Häcker1, Jacob Michael Mayer1
1Institute of Chemical Engineering and Environmental Technology, Graz University of Technology, Inffeldgasse 25/C, 8010 Graz, Austria.
Molecules (Basel, Switzerland)
|September 14, 2024
概括
来自天然类的新型欧溶剂有效地从水溶液中提取芳香性化物. 基于坎的溶剂具有较低的粘度和良好的提取产量,克服了传统系统的局限性.
科学领域:
- 绿色化学 绿色化学
- 分离科学 分离科学
- 超分子化学 超分子化学
背景情况:
- 类是丰富的天然产品,具有作为可持续化学原料的潜力.
- 欧特克系统为各种应用提供可调整的物理化学特性.
- 芳香性化物是存在于调味品,香料和药品中的有价值化合物.
研究的目的:
- 为了合成和表征基于二元烯酸的欧性溶剂.
- 评估它们在提取香草素,注射剂和p-hydroxybenzaldehyde中的性能.
- 研究这些新型溶剂的物理化学特性和稳定性.
主要方法:
- 合成和固体-液体平衡 (SLE) 确定欧特克系统.
- 从酸性水溶液中提取溶剂的实验.
- 使用高性能液态染色学 (HPLC) 量化阿尔代提取.
- 分析相互溶解度 (卡尔·菲舍尔定位,TOC) 和物理化学性质 (密度,粘度).
主要成果:
- 所有合成的eutectic系统都表现出强烈的疏水性,水和和溶剂损失最小.
- 与基于坎的溶剂相比,基于芬的溶剂显示出更高的提取效率.
- 乙醇:薄荷 (50:50 mol.%) 系统实现了素 (>95%) 和甲 (>93%) 的最高提取率.
- 芬科尔:1-多德卡诺尔 (80:20 mol.%) 溶剂证明了对p-基甲 (93.08%) 的优异提取.
- 坎:硫醇溶剂提供显著较低的粘度 (3.436 mPas),具有高提取效率的香 (>95%) 和甲 (>93%).
结论:
- 基于二进制烯酸的欧溶剂是芳香性化物提取的有效和可持续的替代品.
- 溶剂的选择会影响提取效率,粘度和疏水性.
- 坎 - 蒂摩尔欧特克系统是一个有前途的低粘度选项,具有高提取性能.
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