母亲对后代的影响食物过敏食物过敏
Hwa Yeong Lee1,2, Tanuza Nazmul1, Jinggang Lan1
1Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Boston, Massachusetts, USA.
Immunological reviews
|September 14, 2024
概括
饮食和母乳等母亲因素显著影响孩子患过敏的风险. 了解这些早期生活相互作用是预防食物过敏和促进免疫耐受性的关键.
科学领域:
- 免疫学 免疫学 免疫学
- 新生儿研究新生儿研究
- 过敏的病原发生和发病.
背景情况:
- 全球过敏患病率上升,特别是在生命早期.
- 在了解个体对过敏的敏感性方面存在重大知识差距.
- 新生儿免疫系统在调解耐受性和过敏方面的作用至关重要.
研究的目的:
- 审查最近 (10年) 关于影响后代过敏的母亲因素的研究.
- 专注于食物过敏,严重的过敏反应.
- 扩大对食物过敏发展中的母婴相互作用的理解.
主要方法:
- 关于过去10年发表的研究的文献综述.
- 分析母亲的因素,包括母乳,饮食,抗体和微生物群.
- 对它们对后代过敏发展的影响的综合研究.
主要成果:
- 确定了可能调节后代过敏的关键母性因素.
- 突出了母乳,母亲的饮食,抗体和微生物群的作用.
- 强调需要对这些相互作用进行进一步研究.
结论:
- 母亲因素在决定后代对过敏的易感性方面发挥着重要作用.
- 对母婴相互作用的进一步调查对于了解食物过敏的发病因子至关重要.
- 这种知识可以为预防过敏和发展免疫耐受性的策略提供信息.
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