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通过分子动力学模拟,研究SND1和MTDH之间的关键残留突变的结合机制和影响

Senchen Liu1, Xiafei Hao2, Dongqiang Miao1

  • 1School of Mathematics & Physics, Hebei University of Engineering, Handan 056038, China.

The journal of physical chemistry. B
|September 14, 2024
PubMed
概括

研究人员探索了乳腺癌中甲素 (MTDH) 和葡萄球菌核酶域1 (SND1) 之间的结合机制. 关键的残留突变显著改变了结合相互作用,揭示了开发新抗乳腺癌药物至关重要的原子细节.

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