在不同诊断指南中,隔离的透气性高血压和心血管结果:系统性审查和元分析
Abhimanyu Agarwal1, Mohamed A Mostafa2, Muhammad Imtiaz Ahmad3
1Section on Cardiovascular Medicine, Department of Medicine, Epidemiological Cardiology Research Center (EPICARE), Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, NC, 27157, USA. abhsworld@gmail.com.
概括
隔离性透气高血压 (IDH) 增加了心血管疾病 (CVD) 的风险,较高的透气压切断线显示出更大的风险. 该协会受到研究设计,性别和种族的影响.
科学领域:
- 心脏病学 心脏病学
- 高血压研究 高血压研究
- 公共卫生 公共卫生
背景情况:
- 隔离性透气高血压 (IDH) 是一种独特的高血压状况.
- 了解IDH对心血管的影响对于风险分层和管理至关重要.
研究的目的:
- 系统地审查和元分析隔离性腹筋高血压 (IDH) 对心血管结果的影响.
- 通过不同高血压诊断指南,比较IDH与心血管风险的相关性.
主要方法:
- 来自PubMed和SCOPUS数据库的英语文章的系统审查和元分析.
- 在2023年7月31日之前搜索了研究IDH与心血管结果之间的关联.
- 包括19项不同样本大小和设计的研究,评估了ACC/AHA,JNC7和NICE/ESC指南.
主要成果:
- 使用JNC7指南的队列研究表明,IDH与心血管疾病 (CVD) 风险增加 (HR:1.45),心血管疾病死亡率 (HR:1.54) 和冠状动脉心脏病 (CHD) 风险增加 (HR:1.65) 有关.
- 与ACC/AHA关于心血管疾病风险 (HR: 1.16) 和心血管疾病死亡率 (HR: 1.10) 的指南相比,相关性较弱.
- 亚组分析显示出基于年龄,性别和种族的结果差异;横截面研究显示没有显著的关联.
结论:
- 隔离性透气性高血压与心血管疾病风险显著增加有关.
- 较高的舒张血压值与心血管风险升高相关.
- 观察到的关联是由研究设计,性别和种族调节的,突出显示了IDH风险评估的复杂性.
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