杆菌和:有没有关系?
Ahmed Abdelfattah Afify1, Hanan Mohamed Ahmed Saleh2, Abeer Farrag Hussein2
1Dermatology, venereology and andrology department, Faculty of medicine, Ain Shams University, Cairo, Egypt. dr.ahmed_abdelfattah1982@yahoo.com.
杆菌 (H. pylori) 感染在病 (AV) 患者中很普遍,并且与疾病的严重程度有关. 这项研究发现,与轻度病例和健康对照相比,在严重的AV病例中,H. pylori的发病率更高.
科学领域:
- 皮肤病学 皮肤病学
- 微生物学 微生物学
- 胃肠病学 胃肠病学
背景情况:
- 杆菌 (H. pylori) 是一种胃病原体,与各种肠外疾病有关.
- 以前的研究表明,H. pylori感染和的严重程度之间存在潜在的关联.
- 关于H. pylori感染对不同严重程度的AV感染的影响的数据有限.
研究的目的:
- 为了调查H. pylori感染和 (AV) 之间的关联.
- 为了将H. pylori感染率与的严重程度相关联.
主要方法:
- 一项病例控制研究涉及45名AV患者和45名健康对照.
- 在所有参与者中使用ELISA套件测试H. pylori便抗原和血清IgG抗体.
主要成果:
- 总体而言,H. pylori感染率为便抗原38.9%,血清抗体45.6%.
- 与健康对照组相比,AV患者的H.pylori感染率明显较高 (P < 0.001,P = 0.006).与健康对照组相比,AV患者的H.pylori感染率明显较高.
- 抗原和抗体的H. pylori感染率与的严重程度有显著的相关性 (P < 0.001).
结论:
- 在患者中,H. pylori感染非常普遍,这表明它在皮肤病的发病过程中发挥了作用.
- 患有严重的患者表现出比患有轻度或健康个体更高的H. pylori感染标志物的比率.
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