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Updated: Jul 15, 2026

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在ApoE小鼠模型中,CCN4 (WISP-1) 降低了细胞亡和动脉样硬化斑块负担

Helen Williams1, Steven Simmonds2, Andrew Bond1

  • 1Bristol Heart Institute, Bristol Medical School, University of Bristol, UK.

Atherosclerosis
|September 14, 2024
PubMed
概括

CCN4 (WISP-1) 蛋白质促进细胞存活,减少动脉样硬化斑块的进展和严重程度. 它的缺乏会增加亡和斑块负担,突出其治疗心血管疾病的治疗潜力.

关键词:
亚脂蛋白 E 是一种阿波利波蛋白.细胞灭亡 (apoptosis) 是一种死亡的过程.动脉样硬化是一种动脉样硬化.在CCN-4/WISP-1中使用.巨细胞是一个巨细胞.在VSMCs中.没有路径的路径.

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