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Feng Cao¹, Shengmin Lu¹

¹College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Zhejiang Provincial Key Laboratory of Fruit and Vegetables Postharvest and Processing Technology, Ministry of Agriculture and Rural Affairs Key Laboratory of Post-Harvest Handling of Fruits, Institute of Food Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.

|September 14, 2024

概括

研究人员开发了多孔粉载体,以有效地加载和维持纳林金 (NAR) 的释放. 修改后的粉载体具有更高的替代度,提供了更好的保护和更慢的释放naringin.

科学领域:

食品科学与技术食品科学与技术
材料科学材料科学材料科学
生物技术是生物技术.

背景情况:

类黄类的纳林因 (NAR) 具有潜在的健康益处,但需要有效的输送系统.
基于粉的材料由于其生物相容性和生物降解性,为药物和营养物质的输送提供了一个有前途的平台.

研究的目的:

开发和表征多孔粉 (PS) 和酸 (OSA) 化PS (OSAPS) 复合物,用于纳林 (NAR) 载荷和持续释放.
研究OSAPS的替代度 (DS) 对NAR加载效率和体外释放动力学的影响.

主要方法:

在乙醇溶液中使用超声波方法将NAR与PS和OSAPS复合.
综合体的微形态,结构和热性质的表征.
在实验室中,在模拟的消化条件下从复合物中释放NAR的研究.

主要成果:

在无形形式中,NAR已成功加载到PS和OSAPS.
随着OSAPS的DS,NAR的加载效率有所提高,在DS 0.0427.7上达到86.85%,达到86.85%.
复合物的NAR释放率高于自由NAR,但随着DS的增加而下降,表明OSAPS的保护作用.

结论:

具有较高DS的OSAPS是有效的载体,可以有效地进行轮加载和持续释放.
开发的基于粉的输送系统扩大了对改性粉和类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类类
这项研究提供了一种新的方法,用于构建基于粉的载体,用于增强的输送系统.

关键词:

替代的几度替代的几度在体外消化过程中消化.装载方式装载方式改性多孔粉改性多孔粉纳林丁 (Naringin) 是一个古老的语言.八烯酸酸无水化物 (Octenyl succinic 结构的表征结构的表征.

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