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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
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Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
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炎症性饮食模式与乳腺特征之间的关联

Shadi Azam1, Sarah Asad2, Saurabh D Chitnis2

  • 1Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States.

The Journal of nutrition
|September 14, 2024
PubMed
概括

减轻炎症 (EDIP) 的饮食模式与较低的乳腺扫描密度有关,乳腺癌的危险因素. 这种关联主要是由体重指数 (BMI) 解释的.

关键词:
在EDIP分数中,EDIP的分数是:护士健康研究研究乳腺密度 乳腺密度饮食模式 饮食模式经验性的饮食炎症模式乳腺图像密度 乳腺图像密度哺乳镜的特征 哺乳镜的特征

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科学领域:

  • 营养和癌症研究 营养和癌症研究
  • 放射学和成像学 放射学和成像学
  • 流行病学 流行病学

背景情况:

  • 经验性饮食炎症模式评分 (EDIP) 反映了饮食的抗炎潜力,并与脂肪和乳腺癌 (BC) 风险有关.
  • 乳腺扫描密度 (MD) 是乳腺癌的一个重要风险因素.

研究的目的:

  • 为了研究EDIP和乳腺特征之间的关系.
  • 为了确定脂肪是否调解EDIP和乳腺特征之间的关联.

主要方法:

  • 对来自护士健康研究 (NHS) 和NHSII没有BC诊断的4145名参与者的分析.
  • 使用食物频率问卷和乳房扫描密度 (MD) 参数评估累积平均EDIP.
  • 使用BMI应用多变量调整的线性回归和中介分析.

主要成果:

  • EDIP与百分比乳腺扫描密度 (MD) (β = -0.57) 相反相关.
  • 身体质量指数 (BMI) 中介68%的EDIP和百分比MD之间的关联.
  • 在对BMI进行调整后,EDIP显示了与非密集的乳房区域的积极关联.

结论:

  • 在EDIP得分与百分比乳腺扫描密度相反相关.
  • EDIP与乳房图像特征之间的关联在很大程度上是由BMI调解的.
  • 影响炎症的饮食模式可能会通过乳房扫描密度和脂肪度影响乳腺癌风险.