在大麻种子油脂体中封装大麻二醇
Zhaoxiang Ma1, Johannes H Bitter2, Remko M Boom3
1Biobased Chemistry and Technology, Wageningen University and Research, Bornse Weilanden 9, PO Box 17, 6708 WG Wageningen, the Netherlands; Food Process Engineering, Wageningen University and Research, Bornse Weilanden 9, PO Box 17, 6708 WG Wageningen, the Netherlands.
Food research international (Ottawa, Ont.)
|September 14, 2024
概括
油脂体有效地封装了大麻 (CBD),作为缓释载体. 它们的结构保持稳定,不受CBD或加工的影响,使得疏水化合物的各种应用成为可能.
科学领域:
- 食品科学与技术 食品科学与技术
- 生物技术是生物技术.
- 材料科学 材料科学 材料科学
背景情况:
- 油体,油种子中的天然脂质滴,形成稳定的油/水乳液.
- 它们的结构,脂质核心与脂蛋白单层,是封装疏水化合物的理想选择.
- 大麻素 (CBD) 是一种疏水性化合物,需要液化才能有效封装.
研究的目的:
- 为了研究油脂体作为大麻 (CBD) 封装的载体.
- 评估不同液化方法对CBD封装效率的影响.
- 评估CBD载荷的油脂体的体外释放特征和稳定性.
主要方法:
- 油从油中提取出来,并形成分散物.
- 大麻二醇 (CBD) 通过加热或在乙醇中预溶解液化.
- CBD被封装成油脂体,并确定封装效率.
- 进行了体外消化分析,以研究CBD释放.
主要成果:
- 加热和乙醇预溶解方法都产生了良好的CBD封装效率.
- 由于和,随着CBD与脂质比率的增加,封装效率下降.
- 油体在体外消化过程中表现出缓慢而稳定的CBD释放.
- 油脂酶封装和消化特性不受CBD,加热或乙醇的影响.
结论:
- 油脂体是对像CBD这样的疏水化合物的有效载体,具有缓释性质.
- 封装过程和油脂体稳定性是强大的,耐受CBD和常见的加工处理.
- 这些发现支持了脂体作为各种行业的输送系统的广泛应用.
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