临床因素与唾液流速相关的成年人与壮成长症
Renata C Campelo1, Bruno B Benatti1, Joana A B de Sousa1
1School of Dentistry, Federal University of Maranhão, São Luís, Brazil.
Oral surgery, oral medicine, oral pathology and oral radiology
|September 14, 2024
概括
患有壮症的成年人表现出更高的未刺激的唾液流 (USF). 年龄较大与这些患者的USF减少有关,突出显示了壮病中潜在的唾液功能障碍.
科学领域:
- 内分泌学 在内分泌学.
- 口腔医学是指口腔医学.
- 唾液腺生理学 唾液腺生理学
背景情况:
- 巨症是一种由生长激素过量引起的疾病,可以影响各种身体功能.
- 唾液流变化是壮病的潜在但未被充分研究的并发症.
- 了解液功能在壮病中对于全面的患者护理至关重要.
研究的目的:
- 为了研究非刺激的唾液流 (USF) 和刺激的唾液流 (SSF) 在成年人壮症.
- 为了确定与积病患者的唾液流异常相关的临床因素.
- 为了比较积病患者和对照组之间的唾液流量参数.
主要方法:
- 一个病例对照研究,涉及29名成年人患有巨病和29名年龄和性别匹配的对照.
- 收集社会人口统计数据,生活习惯和临床测量,包括BMI,宫和腹部周长.
- 使用未配对的t测试,皮尔森相关性和多变量回归模型进行统计分析,以评估USF和SSF.
主要成果:
- 与对照组 (0.22毫升/分钟) 相比,壮症组显示出明显更高的USF (0.50毫升/分钟).
- 刺激的唾液流 (SSF) 与宫周长呈正相关性 (r = 0.470,P = .010).
- 巨症独立地与USF增加有关 (标准化系数 = 0.780,P = .039),而年龄较大与USF减少有关 (标准化系数 = -0.333,P = .013).
结论:
- 被诊断为壮症的成年人呈现高高的非刺激的唾液流量.
- 随着年龄的增长,与一般人群中未经刺激的唾液流量减少以及潜在的壮症患者中相关的重要因素.
- 这些发现强调了壮症对唾液腺功能的影响,并强调了年龄作为唾液输出的调节器.
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