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Updated: Jun 13, 2025

Three Dimensional Cultures: A Tool To Study Normal Acinar Architecture vs. Malignant Transformation Of Breast Cells
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通过Ck2控制和Src/Akt/Stat3减弱,Mcam可以稳定一种类似于光线原始的乳腺癌细胞状态

Ozlen Balcioglu1,2, Brooke L Gates1,2, David W Freeman1,2

  • 1Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 84112, USA.

NPJ breast cancer
|September 14, 2024
PubMed
概括

细胞表面的糖蛋白MCAM维持着原生细胞状态,驱动着基底类乳腺癌. 抑制MCAM,CK2或STAT3可能为内分泌抵抗性乳腺癌提供新的治疗策略.

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