体重指数的变化及其与SARS-CoV-2感染的关联:现实世界的分析
Jithin Sam Varghese1,2, Yi Guo3, Mohammed K Ali1,2,4
1Emory Global Diabetes Research Center of Woodruff Health Sciences Center and Emory University, Atlanta, GA, USA.
International journal of obesity (2005)
|September 14, 2024
概括
身体质量指数 (BMI) 轨迹在有或没有SARS-CoV-2感染的个体之间有所不同. 需要进一步的研究来了解COVID-19后的体重变化.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 由于COVID-19的流行,人们对潜在的长期健康影响感到担忧,包括身体质量指数 (BMI) 的变化.
- 了解与SARS-CoV-2感染有关的BMI波动对于公共卫生战略至关重要.
研究的目的:
- 为了研究成人BMI的变化,有或没有SARS-CoV-2感染.
- 为了比较感染者,未感染者和历史对照组之间的BMI轨迹.
主要方法:
- 利用来自OneFlorida+临床研究网络的现实数据.
- 通过使用目标试验方法对SARS-CoV-2暴露,未暴露和历史控制队伍的BMI随时间变化进行比较.
- 分析了249,743名参与者的电子健康记录中的客观身高和体重指标.
主要成果:
- 与未暴露组相比,在随访开始时,SARS-CoV-2感染的个体的平均BMI略高.
- 在100天的SARS-CoV-2暴露队列中,BMI保持稳定,在未暴露队列中下降,并在历史队列中增加.
- 观察到的BMI差异在各个子组中是一致的,但在男性和老年人中有一些例外.
结论:
- 平均BMI轨迹在感染SARS-CoV-2和没有感染的个体之间有显著差异.
- 在SARS-CoV-2感染后体重变化的潜在机制和临床影响需要进一步调查.
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