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与COVID-19检测相关的创伤性CSF鼻:一个病例系列和系统审查

Shireen A Samargandy^1,2,3, Christian G Fritz⁴, David Ahmadian⁵

¹Department of Otolaryngology-Head and Neck Surgery, The University of Arizona, Tucson, AZ, USA.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

|September 15, 2024

概括

创伤性脑脊髓液 (CSF) 泄漏可能发生在鼻抽样检测SARS-CoV-2后. 内镜外科修复是有效的管理这些泄漏,特别是当脑膜炎的存在.

科学领域:

神经学神经学
耳鼻喉科耳鼻喉科耳鼻喉科
传染性疾病传染性疾病

背景情况:

用于检测SARS-CoV-2的鼻抽样可以导致创伤性前额头底CSF泄漏.
本研究介绍了迄今为止关于这种并发症的最大的案例系列,并补充了系统的文献审查.

研究的目的:

分析COVID-19的鼻抽样后的CSF泄漏的呈现,风险因素和管理.
澄清这些泄漏的临床过程和结果,包括脑膜炎的影响.

主要方法:

创伤性前头骨基底CSF泄漏的回顾性多机构案例系列,有COVID-19抽样史.
对相关数据库的系统文献审查.

主要成果:

34名患者在抽样后发现了CSF泄漏;女性更容易受到影响.
常见的泄漏点包括cribriform板 (52.9%). 四名患者 (11.8%) 患有脑膜炎.
泄漏检测的中位时间为4周. 脑膜炎患者的泄漏时间更长. 在92.9%的病例中,内镜修复成功.

结论:

诊断性鼻抽样可以导致前头骨底部的脑脊液泄漏.
及时内镜内外科修复是对这些CSF泄漏的推管理.

关键词:

在 COVID-19 疫情中,在CSF中,管是管.脑脊髓的鼻发作脑脊髓的鼻发作产生的 CSF 泄漏是有毒的鼻子抽样测试鼻子抽样测试创伤性CSF泄漏创伤性CSF泄漏

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