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揭露富可桑丁的命运:体外胃肠道消化对生物可访问性,抗氧化能力,颜色变化和代谢物概况的影响
Zuhaili Yusof1, Vuanghao Lim2, Nicholas M H Khong3
1School of Science, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, 47500, Selangor Darul Ehsan, Malaysia.
Food chemistry
|September 15, 2024
概括
富可丁在消化过程中表现出良好的生物可访问性和抗氧化活性,具有显著的颜色变化和代谢物形成. 这些发现支持其作为功能性食品成分的潜力.
科学领域:
- 营养科学 营养科学
- 食品化学 食品化学
- 生物化学 生物化学
背景情况:
- 在消化过程中对富可桑丁的行为了解有限,这阻碍了其作为功能成分的应用.
- 富可丁是一种海洋类胡卜素,以其潜在的健康益处而闻名.
- 调查消化系统的变化对于优化富可桑的疗效至关重要.
研究的目的:
- 评估体外消化对富可桑生物可访问性的影响.
- 为了评估富可桑抗氧化活性和颜色的变化.
- 为了确定在消化过程中形成的代谢物及其与功能性质的相关性.
主要方法:
- 在体外胃肠道消化模型模拟口腔,胃和肠道阶段.
- 使用分析方法量化富可桑的生物可访问性.
- 使用已建立的测定方法测量抗氧化剂活性.
- 测色分析以确定颜色变化 (ΔE*).
- 液体染色学-并联质谱学 (LC-MS/MS) 用于代谢分析.
主要成果:
- 在胃消化过程中观察到的富可桑丁的最高生物可访问性 (0.03 ± 0.00 mg/mL).
- 抗氧化活性在胃阶段达到峰值,并在消化后保持显著 (P <0.05).
- 在所有消化阶段 (2.40-2.86) 观察到显著的颜色变化 (ΔE*).
- 在胃和肠道消化过程中,LC-MS/MS确定了15种代谢物,主要是酸.
- 代谢物概况与生物可访问性,抗氧化活性和颜色变化有显著的相关性.
结论:
- 在整个模拟消化过程中,富可丁表现出显著的生物可访问性和抗氧化能力.
- 消化过程导致富可桑颜色发生显著变化,并导致代谢物形成.
- 已识别的代谢物与富可桑的功能性质有关,证实其作为功能性食品成分的潜力.
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