在环境相关的度下,6-PPD素对C. elegans的寿命造成损害:通过抑制线粒体UPR反应的机械洞察力

Xin Hua1, Dayong Wang2

  • 1Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Medical School, Southeast University, Nanjing, China.

PubMed
概括

在C. elegans中,6-PPD (6-PPDQ) 毒性与抑制的线粒体未折叠蛋白反应 (mt UPR) 有关. 基斯甲基化通路调节这种反应,影响在6-PPDQ暴露下寿命和线粒体功能.

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