流体过载与儿科重症监护病房的死亡率和发病率之间的关系
Hilmi Bayirli1, Nazan Ulgen Tekerek2, Alper Koker2
1Department of Pediatrics, Akdeniz University Faculty of Medicine, Antalya, Turkey.
Medicina intensiva
|September 15, 2024
概括
重症儿童的液体过载显著增加了死亡风险. 峰值和累积液体过载是独立的风险因素,超过10%的累积过载与3.9倍高的死亡率有关.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 临床结果研究研究的临床结果.
- 在重症监护室的流体管理.
背景情况:
- 流体过载是重症儿童常见的并发症.
- 流体过载对该群体死亡率和发病率的影响需要进一步调查.
研究的目的:
- 调查儿科重症监护室 (PICU) 患者的流体过载和临床结果之间的关系.
- 确定与死亡率相关的特定液体过载指标 (早期,峰值,累积).
主要方法:
- 对2019年至2021年期间入住PICU的儿童进行了回顾性队列研究.
- 与死亡率相关的早期,峰值和累积液体过载的分析.
- 对包括年龄和疾病严重程度在内的混因素进行统计调整.
主要成果:
- 死亡率为11.7%,其中死亡率为11.7%.
- 峰值和累积液体过载分别与死亡率增加有关 (aOR分别为1.15和1.10).
- 10%或以上的累积液体过载与3.9倍的死亡率增加有关,并且与ICU和无呼吸器日负相关.
结论:
- 峰值和累积液体过载是危急儿童死亡的独立风险因素.
- 流体过载与患病率增加有关,包括减少ICU和无呼吸器日.
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