患有缺水性外皮形发育不良的成长个体的功能:一项纵向研究
Meili Ding1,2, Yanfeng Kang3, Man Qin1
1Department of Pediatric Dentistry, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.
与对照组相比,低水分性外皮发育不良症 (HED) 患者表现出较低的功能和效率. 假肢康复改善了从童年到青春期的HED个体的功能.
科学领域:
- 口腔生物学 口腔生物学
- 生物医学工程 生物医学工程
- 遗传学 遗传学 是一个
背景情况:
- 缺水性外皮形症 (HED) 是一种遗传性疾病,其特征是外皮结构的缺陷发育,导致牙缺失 (oligodontia/anodontia).
- 患有HED的患者通常需要假肢康复,例如假牙,以恢复功能.
- 评估假肢康复对正在成长的HED患者口功能的长期影响至关重要.
研究的目的:
- 在接受假肢康复的中国HED患者中初步评估功能变化.
- 为了比较HED患者的性能与从童年到青春期的健康对照.
- 分析假肢康复对肌肉活动和效率随时间推移的影响.
主要方法:
- 一项纵向研究涉及10名HED患者和健康儿童和青少年的对照组.
- 表面电肌图 (EMG) 记录了按摩器 (MM) 和前肌 (TA) 肌肉活动在紧握和时.
- 分析包括EMG活动,不对称指数 (As),活动指数 (Ac),周期,效率的光谱测量和主观问卷.
主要成果:
- 与儿童和青少年时期的对照组相比,HED患者的EMG活动和效率较低,不对称性 (As) 更高.
- 刺激改善了TA肌肉活动,并减少了HED青少年的不对称性.
- HED青少年表现出更突出的TA肌肉活动.
结论:
- 与有牙的个体相比,正在成长的HED患者表现出功能性较差的能力.
- 从童年到青春期,HED患者和对照人群之间的功能的功能差距缩小了,这表明随着年龄和康复的增长,一些适应性改善.
- 假肢康复在改善HED患者发育期的功能方面发挥着作用.
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