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身体疾病与随后的精神疾病之间的关联:在基于人口的队列队列中进行了纵向研究
Natalie C Momen1, Søren Dinesen Østergaard2,3, Uffe Heide-Jorgensen1
1Department of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.
概括
大多数身体疾病显著增加患上后来的精神疾病的风险. 这项大规模的研究强调了临床医生监测身体疾病患者的心理健康状况的关键需求.
科学领域:
- 流行病学 流行病学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 现有的关于身体疾病和随后的精神障碍的研究范围有限,通常只检查少数条件对或仅关注相对风险.
- 对身体健康和精神健康之间的双向关系的全面理解对于整体的患者护理至关重要.
研究的目的:
- 系统地调查各种身体疾病与随后发展精神疾病的风险之间的联系.
- 提供对相对和绝对风险的详细分析,考虑各种身体疾病类别和精神疾病诊断.
主要方法:
- 丹麦的一项基于人口的队列研究,涉及2000年至2021年期间的7,673,978人,随访时间为1.193亿人年.
- 评估九个广泛的身体疾病类别 (包括心血管,内分泌,呼吸道,肌肉骨和癌症) 和十个ICD-10精神疾病分类.
- 用Poisson回归来计算发病率比率 (IRR) 和Aalen-Johansen估计器来估计绝对风险,调整年龄,性别和日历时间.
主要成果:
- 在随访期间,共有646,171人 (8.4%) 患上精神障碍.
- 除癌症外,所有研究的身体疾病都与随后精神疾病的风险增加有关 (中位数IRR: 1.51).
- 肌肉骨疾病的IRR最高 (1.84),呼吸系统疾病的累积发病率最高 (10.19%) 在诊断后15年内.
结论:
- 这项研究证实,大多数身体疾病与明显增加患精神疾病的风险有关.
- 这些发现强调了综合护理的重要性,敦促临床医生保持警,警身体疾病患者出现二次心理健康状况.
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