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Updated: Jun 13, 2025

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一个新的零HLA-B等位基因,B*40:510N,是由于2个外体中的单个核酸删除导致的

Xian-Xin Zhong1, Zhan-Rou Quan2

  • 1Department of Clinical Laboratory, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, China.

HLA
|September 16, 2024
PubMed
概括

由于HLA-B*40:01:02:01基因的15号代号中单个核酸被删除,发现了一种新型的零等位基因HLA-B*40:510N. 这一发现扩大了已知的人类白细胞抗原 (HLA) 基因谱.

关键词:
在HLA类型的类型化中.HLA-B*40:510NN 这是一个很好的方法.新型的零等位基因

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Exon Recombination02:32

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The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
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