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Updated: Jun 13, 2025

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生物制药配方中的替代性缓冲系统及其对蛋白质稳定性的影响

Blaž Lebar1,2, Mitja Zidar2, Janez Mravljak1

  • 1University of Ljubljana Faculty of Pharmacy, Department of Pharmaceutical Chemistry, SI-1000 Ljubljana Slovenia.

Acta pharmaceutica (Zagreb, Croatia)
|September 16, 2024
PubMed
概括

替代性缓冲系统显著影响生物制药稳定性. 氨酸/酸盐缓冲剂在解压力期间保持蛋白质稳定性方面表现有希望,比单克隆抗体 (mAbs) 的传统选择提供更高的性能.

关键词:
聚合物 聚合物 聚合物其他替代性缓冲器生物制药制品 生物制药制品缓冲区的缓冲区是一个缓冲区.稳定的稳定性 稳定的稳定性压力就是压力,压力就是压力.

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