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In-vitro Mutagenesis01:16

In-vitro Mutagenesis

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To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
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Life Histories01:29

Life Histories

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Overview
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Synthetic Biology02:55

Synthetic Biology

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Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
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The Scientific Method01:32

The Scientific Method

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The scientific method is a detailed, empirical problem-solving process used by biologists and other scientists. This iterative approach involves formulating a question based on observation, developing a testable potential explanation for the observation (called a hypothesis), making and testing predictions based on the hypothesis, and using the findings to create new hypotheses and predictions.
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...
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Characteristics of Life01:23

Characteristics of Life

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Biology is a natural science that studies life and living organisms, including their structure, function, development, interactions, evolution, distribution, and taxonomy. The field's scope is extensive and divided into several specialized disciplines, such as anatomy, physiology, ethology, genetics, and many more. All living things share a few key traits, including cellular organization, heritable genetic material and the ability to adapt/evolve, metabolism to regulate energy needs, the...
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Hardy-Weinberg Principle01:49

Hardy-Weinberg Principle

71.9K
Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.
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Updated: Jun 13, 2025

An Open Source Technology Platform to Manufacture Hydrogel-Based 3D Culture Models in an Automated and Standardized Fashion
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An Open Source Technology Platform to Manufacture Hydrogel-Based 3D Culture Models in an Automated and Standardized Fashion

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困扰生命科学出版的五个问题 - 以及一个常见的原因.

Duncan E Wright1

  • 1FEBS Letters Editorial Office, Cambridge, UK.

FEBS letters
|September 16, 2024
PubMed
概括

发表在生命科学期刊面临的挑战包括评论员疲劳,欺诈和掠夺性做法. 解决这些问题需要改革"出版或灭亡"文化和研究人员评估系统.

科学领域:

  • 生命科学 生命科学
  • 学术传播学术交流
  • 科学出版科学出版

背景情况:

  • 学术同行评审期刊是生命科学传播的标准.
  • 数字时代带来了诸如评论员疲劳,欺诈,造纸厂,人工智能风险,掠夺性期刊,冲击因子滥用和沙利米切片等问题.
  • 这些问题削弱了科学出版物的质量和完整性.

研究的目的:

  • 提供对数字时代影响学术出版的杂质的全面概述.
  • 讨论拟议和实施的解决方案,以减轻这些问题.
  • 确定"发表或灭亡"文化和研究人员评估的根本原因.

主要方法:

  • 文献综述和科学出版当前问题的分析.
  • 审查伦理问题及其对研究完整性的影响.
  • 在学术评估中讨论系统性问题.

主要成果:

  • 确定了包括评论员疲劳,欺诈,掠夺性出版和滥用期刊指标在内的关键挑战.
  • 突出了人工智能的作用和不道德的做法,如切 salami.
  • 承认"发表或灭亡"的文化和有缺陷的研究人员评估是潜在的系统问题.
关键词:
影响因子的影响因子.造纸厂 造纸厂 造纸厂 是一个在同行评审中进行同行评审.学术出版学术出版活动

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结论:

  • 科学出版的当前问题是更广泛的文化问题的症状.
  • 改革研究人员评估和将重点从数量转移到出版质量是必不可少的.
  • 为了恢复完整性,需要对科学出版物目的的认识进行全球性的改变.