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Updated: Jun 13, 2025

Capture and Identification of RNA-binding Proteins by Using Click Chemistry-assisted RNA-interactome Capture CARIC Strategy
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通过化学结合来获取封闭的RNA

Karolina Bartosik1, Ronald Micura1

  • 1Institute of Organic Chemistry, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innrain 80-82 6020 Innsbruck Austria ronald.micura@uibk.ac.at.

RSC chemical biology
|September 16, 2024
PubMed
概括

研究人员开发了一种新的点击结合方法,用于合成封闭的mRNA类似物. 这种非模板化的方法产生了高达81个核酸的封闭RNA片段,推进了mRNA研究和治疗应用.

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RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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