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Updated: Jun 13, 2025

A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform
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Published on: July 16, 2016

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IGFBP7在T2D捐赠者的小岛上升调,并减少胰岛素分泌

Efraim Westholm1,2, Alexandros Karagiannopoulos1,2, Nicole Kattner3

  • 1Islet Cell Exocytosis, Lund University Diabetes Centre (LUDC), Department of Clinical Sciences-Malmö, Lund University, Malmö, Sweden.

iScience
|September 16, 2024
PubMed
概括

胰岛素样生长因子结合蛋白7 (IGFBP7) 损害了2型糖尿病 (T2D) 的胰岛素分泌. 减少T2D岛屿中的IGFBP7改善了胰岛素分泌,表明IGFBP7是潜在的治疗点.

关键词:
细胞生物学 细胞生物学细胞生理学 细胞生理学生理学 生理学 生理学

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