通过TRAF6-NS1相互作用,ZIKV诱导了TRAF6的P62-介导的自降解

Shengze Zhang1,2, Chuming Luo1,2, Qiqi Chen1,2

  • 1School of Public Health (Shenzhen), Shenzhen Key Laboratory of Pathogenic Microbes and Biosafety, Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, P.R. China.

iScience
|September 16, 2024
PubMed
概括

寨卡病毒 (ZIKV) 感染通过促进其降解来降低瘤亡因子受体相关因子6 (TRAF6) 的水平. TRAF6增强了ZIKV感染和炎症反应,这表明向NS1-TRAF6相互作用可以控制ZIKV.

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