在患有远端恶性阻塞的患者中,通过皮肤穿透肝胆道支架后发生急性胰腺炎的危险因素
Chengzhi Zhang1, Yiming Liu1, Xueliang Zhou1
1Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Quantitative imaging in medicine and surgery
|September 16, 2024
概括
较长的手术时间,反复的胆管出血,手术内扩张和先前的内镜手术增加了穿皮透肝胆道支架 (PTBS) 后急性胰腺炎 (AP) 的风险. 这些因素对于临床医生来说至关重要.
科学领域:
- 干预性放射学 干预性放射学
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
背景情况:
- 皮肤穿透肝胆道支架 (PTBS) 有效治疗恶性胆道阻塞.
- 手术后急性胰腺炎 (AP) 是PTBS后的一个显著并发症.
研究的目的:
- 确定PTBS后AP的独立风险因素.
- 为了告知临床实践和减少AP发生率.
主要方法:
- 对463名因恶性胆道阻塞而接受PTBS患者的回顾性分析.
- 后勤回归分析以确定风险因素和赔率比率 (ORs).
主要成果:
- AP的发生率为10.88%.
- AP的独立风险因素包括反复的胆管出血 (OR=14.370),手术内扩张 (OR=7.848),手术时间>50分钟 (OR=5.783) 和之前的内镜干预 (OR=5.468).
- 性别,年龄,BMI和支架尺寸等因素与AP没有显著相关.
结论:
- 较长的操作时间,手术内扩张,反复的胆道出血和先前的内镜干预是PTBS后AP的重要风险因素.
- 对这些因素的认识可以指导临床实践中的预防策略.
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