偏头痛中与右向左转相关的大脑功能变化:来自休息状态FMRI研究的证据
Wenfei Cao1, Lei Jiao1, Huizhong Zhou1
1Department of Neurology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Frontiers in human neuroscience
|September 16, 2024
概括
偏头痛患者的右向左转移 (RLS) 显示出明显的脑功能变化. 这些变化涉及到本地大脑区域,连接和关键的疼痛处理和调节的网络.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 医疗成像医学成像
背景情况:
- 偏头痛是一种复杂的神经疾病,原因不明.
- 偏头痛和右向左偏移 (RLS) 之间的潜在关联已被建议,但尚未完全理解.
研究的目的:
- 调查RLS的偏头痛患者的大脑功能变化.
- 探索RLS严重程度与大脑功能指标之间的关系.
主要方法:
- 使用的低频波动幅度 (ALFF),分数ALFF (fALFF),区域同质性 (ReHo) 和功能连接性 (FC) 分析.
- 采用基于图形理论的网络分析来评估功能网络.
- 使用皮尔森相关性来检查RLS严重程度和功能指标.
主要成果:
- 患有RLS的偏头痛患者在部区域增加了ALFF,功能连接性发生了变化 (DMN/视觉/腹部注意力网络之间减少,前侧对面/腹部注意力网络增加).
- 网络分析显示,在特定的大脑区域 (例如,前骨,岛骨,回) 的节点效率和中心性发生了变化.
- 在某些地区的ALFF/中心性和RLS严重程度之间发现的相关性.
结论:
- 患有RLS的偏头痛患者表现出显著的大脑功能改变.
- 这些变化影响了大脑局部区域,功能连接和参与疼痛感知和调节的网络.
更多相关视频
08:36Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
Published on: March 21, 2019
7.2K
13:12Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
Published on: August 12, 2019
45.2K
相关概念视频
01:14Brain Imaging
219
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
219
01:24Magnetic Resonance Imaging
5.0K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
5.0K