相关实验视频
Updated: Aug 3, 2026

08:58
Murine Kidney Transplant Technique
Published on: October 20, 2015
16.0K
对瘤切除术和捐赠切除术后患者的功能进行比较:使用倾向性得分匹配分析的长期结果
Pongsatorn Laksanabunsong1, Thitipat Hansomwong1, Chalairat Suk-Ouichai1
1Division of Urology, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.
Heliyon
|September 16, 2024
概括
接受瘤瘤切除术 (TN) 的患者面临的慢性病 (CKD) 的风险与活着的脏捐赠者 (DN) 相似. 47岁以上的年龄和较低的手术前GFR是腎切除术后CKD的关键风险因素.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 移植 移植 移植 移植
背景情况:
- 慢性病 (CKD) 是手术后的一个显著的长期并发症.
- 在瘤切除术 (TN) 和供体切除术 (DN) 后比较CKD发病率对于患者管理和供体安全至关重要.
研究的目的:
- 为了比较经过TN与DN的患者中CKD的长期发病率.
- 为了确定与经过切除术后发展CKD相关的风险因素.
主要方法:
- 在2000-2018年间对1048名患者 (552名TN,496名DN) 的回顾性分析.
- 每组106名患者的1:1倾向性得分根据年龄和手术前GFR匹配.
- 对CKD发病率和CKD阶段≥3.3的风险因素的评估.
主要成果:
- 在TN (26.4%) 和DN (24.5%) 组之间,CKD发病率没有显著差异 (p=0.308).
- 手术后长达10年的平均GFR没有差异.
- 年龄≥47岁和手术前GFR<100被确定为CKD的危险因素.
结论:
- 在TN后的患者和匹配的活体脏捐赠者之间,CKD的长期风险是可比的.
- 年龄和手术前的GFR是关键因素,应考虑瘤切除术患者的CKD发展风险.
相关概念视频
Bone Marrow Sampling and Transplants
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

