性结肠炎和克罗恩病患者的肠急症负担:现实世界的全球研究
Raja Atreya1, Isabel Redondo2, Petra Streit3
1Medical Department 1, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Crohn's & colitis 360
|September 16, 2024
概括
肠急症显著影响患有炎症性肠病 (IBD) 的患者,包括性结肠炎 (UC) 和克罗恩氏病.
科学领域:
- 胃肠病学 胃肠病学
- 炎症性肠病 (IBD) 研究研究
- 患者报告的结果
背景情况:
- 肠急性是炎症性肠病 (IBD) 的破坏性症状,影响性结肠炎 (UC) 和克罗恩病 (CD) 患者.
- 肠急症对具有不同治疗史的IBD患者的影响需要进一步评估.
- 这项研究调查了IBD患者在不同治疗经验中的肠急症的临床和生活质量负担.
研究的目的:
- 评估IBD患者肠道急症的患病率和负担.
- 评估肠急症对与健康有关的生活质量和工作生产力的影响.
- 为了比较不同治疗组 (天真,一线,经验丰富) 的肠急症负担.
主要方法:
- 在六个国家的胃肠科医生及其IBD患者的横截面调查.
- 根据针对性治疗的经验,患者被分为三组:原始,一线和经验丰富.
- 收集的数据包括患者人口统计,临床特征,治疗史,与健康有关的生活质量和工作生产力.
主要成果:
- 持续性肠急影响17% - 26%的UC和13% - 17%的CD患者,无论治疗.
- 肠急症患者报告了更高的临床和生活质量负担.
- 在所有治疗经验水平上,这种负担仍然很大,医生认为这是一个难以治疗的症状.
结论:
- 肠急性对IBD患者来说是一个重大挑战,影响了他们的生活质量.
- 目前的治疗方法不能完全缓解许多IBD患者的肠急性.
- 需要新的治疗策略,以有效地管理IBD患者的肠急症.
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