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磁纳米粒子和与寒冷大气等离子体的可能协同作用,用于癌症治疗

Xiaofeng Dai¹, Yilin Dai², Yan Zheng²

¹National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Shaanxi Provincial Center for Regenerative Medicine and Surgical Engineering, The First Affiliated Hospital of Xi'an Jiaotong University Xi'an 710061 PR China.

|September 16, 2024

概括

磁纳米粒子 (MNP) 显示出癌症治疗的前景,但面临着挑战. 冷大气等离子体 (CAP) 可能通过改善基因生成和降低对高温治疗的耐药性来提高MNP的疗效.

科学领域:

生物医学工程生物医学工程
纳米技术纳米技术
在瘤学瘤学.

背景情况:

磁纳米粒子 (MNP) 具有有利的特性,如生物相容性和磁性易感性,用于生物医学应用.
由于治疗效率低,高温耐药性和生物安全性问题,MNP的临床转化受到阻碍.

研究的目的:

探索创新策略,以克服基于MNP的癌症治疗的局限性.
研究冷大气等离子体 (CAP) 作为增强MNP治疗潜力的协同作用剂.

主要方法:

划分MNP的抗癌性质和现有的治疗组合.
根据其增强自由基生成和降低高温耐药性的潜力,CAP作为协同作用剂的建议.
探索CAP作为组合疗法的磁性和光源.

主要成果:

美国农业政策可能会增强自由基的产生,这对于癌症治疗至关重要.
CAP可能会减轻高热性耐药性,这是MNP疗法的关键挑战.
CAP可以防止MNP聚合,并作为磁热和光热疗法的双源.

结论:

冷大气等离子体 (CAP) 提出了一个有前途的协同方法,以提高磁纳米粒子 (MNP) 在瘤学中的临床转化.
对CAP-MNP相互作用的进一步研究可能会释放出新的治疗策略,这对两种技术都有互惠的好处.

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