相关实验视频

Updated: Jun 13, 2025

Assessment of Cardiac Morphological and Functional Changes in Mouse Model of Transverse Aortic Constriction by Echocardiographic Imaging

Assessment of Cardiac Morphological and Functional Changes in Mouse Model of Transverse Aortic Constriction by Echocardiographic Imaging

Published on: June 21, 2016

高海拔迁移对心脏结构和功能的影响:一项为期一年的前性研究

Ming-Dan Deng¹, Xin-Jie Zhang¹, Qin Feng¹

¹Department of Ultrasound, The General Hospital of Western Theater Command, Chengdu, Sichuan, China.

Frontiers in physiology

|September 16, 2024

概括

人类迁移到高海拔地区 (HA) 会导致心脏腔的大小和血液体积的减少. 长期暴露于HA会导致心脏功能下降和肺动脉压力增加.

科学领域:

心脏病学心脏病学
高度生理学高度生理学
人类迁移研究人类迁移研究

背景情况:

人类越来越多地迁移到高海拔地区 (HA),需要了解其生理影响.
有限的前性研究存在于心脏变化超过一个月在HA.

研究的目的:

在长期迁移到HA后,研究健康年轻男性的心脏结构和功能变化.
为了比较不同HA水平 (3600-4000m vs. 4000-4700m) 对心脏参数的影响.

主要方法:

对122名健康的年轻男性迁移到HA进行前性研究.
在海平面,迁移后1个月和1年内进行心声测量.
有两个组:低HA (3600-4000米) 和高HA (4000-4700米).

主要成果:

在HA组1个月和1年后,所有心室的大小都减少了,在高HA组更显著.
1个月后双管管管透缩功能下降;1年后心功能下降.
随着高度和暴露时间的增加,观察到肺动脉扩张和缩压的增加,下静脉腔直径的减少以及血流的减少.

结论:

一年HA迁移与血液体积减少和缺氧肺血管收缩有关.
这些因素有助于心室大小的减少和轻微的双心室功能下降.
HA迁移会诱导显著的心脏结构和功能适应.

关键词:

心脏功能是指心脏功能.进行心脏重塑.超声心电图 (Echocardiography) 是一种心声回声仪.高海拔的高海拔地区.缺氧缺氧是指缺氧的情况.

更多相关视频

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects

Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects

Published on: February 12, 2021

相关概念视频

Factors Affecting Respiration

Factors Affecting Respiration

Respiration is a crucial physiological function involving exchanging oxygen (O2) and carbon dioxide (CO2) between an organism and its environment. Various factors can impact this essential process:

Exercise and Cardiac Output

Exercise and Cardiac Output

Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...